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pentobarbital will decrease the level or effect of nilotinib by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Check.pentobarbital will increase effects of ifosfamide by affecting hepatic enzyme CYP2B6 metabolism. Use Caution/Keep an eye on. Coadministration of ifosfamide with CYP2B6 inducers may possibly maximize metabolism o